rutiletype titanium dioxide manufacturer

Anatase titanium dioxide nanoparticles (ATDNs) have emerged as a fascinating material due to their unique properties and vast potential applications. These nanoparticles are derived from the anatase form of titanium dioxide, which is known for its high photocatalytic activity, stability, and biocompatibility. As a result, ATDNs are finding widespread use in various fields, including cosmetics, healthcare, energy, and environmental remediation.

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In a study published in the journal Environmental Toxicology and Pharmacology in 2020, researchers examined the effects of food additives titanium dioxide and silica on the intestinal tract by grouping and feeding mice three different food-grade particles — micro-TiO2, nano-TiO2, and nano-SiO2.  With all three groups, researchers observed changes in the gut microbiota, particularly mucus-associated bacteria. Furthermore, all three groups experienced inflammatory damage to the intestine, but the nano-TiO2 displayed the most pronounced changes. The researchers wrote: “Our results suggest that the toxic effects on the intestine were due to reduced intestinal mucus barrier function and an increase in metabolite lipopolysaccharides which activated the expression of inflammatory factors downstream. In mice exposed to nano-TiO2, the intestinal PKC/TLR4/NF-κB signaling pathway was activated. These findings will raise awareness of toxicities associated with the use of food-grade TiO2 and SiO2.”

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